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Article

The role of glycine residues at the C-terminal peptide segment in antinociceptive activity: a molecular dynamics simulation.

Journal of molecular modeling - 1 Mar 2013

Zhao Yong-Shan, Zhang Rong, Xu Yang, Cui Yong, Liu Yan-Feng, Song Yong-Bo, Zhang Hong-Xing, Zhang Jing-Hai

Abstract excerpt

Elucidating structural determinants in the functional regions of toxins can provide useful knowledge for designing novel analgesic peptides. Glycine residues at the C-terminal region of the neurotoxin BmK AGP-SYPU2 from the scorpion Buthus martensii Karsch (BmK) have been shown to be crucial to its analgesic activity. However, there has been no research on the structure-function relationship between the...

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Identifiers

PMID: 23179767
DOI: 10.1007/s00894-012-1666-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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