Article
[Genetic polymorphisms as tool indicators for individual vulnerability to smoking behaviour].
Medicina clinica - 19 Jan 2013
Barrot Carme, Sánchez Cristina, Abellana Rosa, Ortega Montserrat, Gené Manuel
Abstract excerpt
BACKGROUND AND OBJECTIVES: In line with genetic and pharmacological studies suggesting that neurotransmitter pathways play a role in nicotine dependence, research was conducted in connection with 4 genetic polymorphisms: OPRM1, TPH1, ADRA2A and HTR1B. This study compares the genotype and allele frequencies in 3 groups (non-smokers, former smokers and smokers) of unrelated individuals (n=490) from Catalonia (north...
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