Article
A comparison of Val81Met and other polymorphisms of alcohol metabolising genes in patients and controls in Northern Spain.
Alcohol (Fayetteville, N.Y.) - 1 Aug 2012
Celorrio David, Bujanda Luis, Caso Carlos, Landabaso Miguel, Oria Juan Carlos, Ogando Javier, de Pancorbo Marian M
Abstract excerpt
The aim of this paper is to study polymorphism in the TH, ADH1B, ADH1C, ALDH2 and CYP2E1 genes so as to ascertain whether it is associated with excessive consumption of alcohol. The SNPs rs6356 of TH, rs1229984, rs2066702 of ADH1B; rs698, rs1693482 of ADH1C; rs671 of ALDH2; , , , , , of CYP2E1 were studied in a sample of 172 high-level patients and 150...