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Article

[Brain neurotransmitter systems gene Polymorphism: the Search for pharmacogenetic markers of efficacy of haloperidol in Russians and Tatars].

Molekuliarnaia biologiia - 1 Jan 2000

Gareeva A E, Kinyasheva K O, Galaktionova D Yu, Sabirov E T, Valinourov R G, Chudinov A V, Zasedatelev A S, Nasedkina T V, Khusnutdinova E K

Abstract excerpt

Antipsychotics are the main drugs for the treatment of severe mental illness--schizophrenia affects about 1% of the population. The mechanism of action of neuroleptics is still up to the end. Several studies in the field of pharmacogenetics confirm enourmous influence of several neurotransmitter systems in the brain on the efficiency and the development of side effects. In this paper, we analyzed the association...

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Share to Antipsychotic Agents
Share to Catechol O-Methyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haloperidol

Share to Receptor, Serotonin, 5-HT2A

Share to Receptors, Dopamine D4

Share to Synaptic Transmission

Share to Tryptophan Hydroxylase

Share to Vesicular Monoamine Transport Proteins

Source

Identifiers

PMID: 26710776
DOI: 10.7868/S0026898415050079

Genes

COMT
DRD4
TPH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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