Article

Changes in DNA Methylation Induced by Dioxins and Dioxin-Like Compounds as Potential Predictor of Disease Risk

2020-10-01

Abstract excerpt

Abstract Dioxins and dioxin-like compounds are persistent organic pollutants (POPs) and technogenic ecotoxicants, the most dangerous of which is 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). A peculiar feature of the considered genotoxicants that distinguishes them from other POPs is hormone-like activity, which is realized through binding to a special cellular protein, the Aryl hydrocarbon Receptor (AhR). In the pr...

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Literature Corpus work: 815a3bdc-3153-56ef-8732-e6729a247558
DOI: 10.1134/s1022795420100063

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