Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between common CYP1A2 polymorphisms and theophylline metabolism in non-smoking healthy volunteers.

Basic & clinical pharmacology & toxicology - 1 Apr 2013

Wang Liqing, Hu Zheyi, Deng Xun, Wang Yong, Zhang Zhongyi, Cheng Ze-Neng

Abstract excerpt

This study was designed to investigate the impact of cytochrome P450 (CYP) 1A2 polymorphisms on theophylline metabolism in a non-smoking healthy male Chinese population. Four polymorphisms CYP1A2 1C (G-3860A), G-3113A, CYP1A2 1F (C-163A) and CYP1A2 1B (C-5347T) were screened in 238 unrelated male volunteers. Then, a single oral 200-mg dose of theophylline was administered to 37 volunteers, who were selected from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Caffeine
Share to China

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromatography, High Pressure Liquid

Share to Cytochrome P-450 CYP1A2

Share to Haplotypes

Share to Theophylline

Share to Young Adult

Source

Identifiers

PMID: 23167834
DOI: 10.1111/bcpt.12038

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between common CYP1A2 polymorphisms and theophylline metabolism in non-smoking healthy volunteers.PMID 23167834Read ↗

The G-113A polymorphism in CYP1A2 affects the caffeine metabolic ratio in a Chinese population.Semantic proximity Read ↗

Phenotype-genotype analysis of CYP1A2 in Japanese patients receiving oral theophylline therapy.Semantic proximity Read ↗

The impact of genetic polymorphisms on CYP1A2 activity in humans: a systematic review and meta-analysis.Semantic proximity Read ↗

The effect of CYP1A2 gene polymorphisms on Theophylline metabolism and chronic obstructive pulmonary disease in Turkish patients.Semantic proximity Read ↗

Influence of genetic polymorphisms, smoking, gender and age on CYP1A2 activity in a Turkish population.Semantic proximity Read ↗

Phenotypic polymorphism and gender-related differences of CYP1A2 activity in a Chinese population.Semantic proximity Read ↗

Associations between CYP2E1 promoter polymorphisms and plasma 1,3-dimethyluric acid/theophylline ratios.Semantic proximity Read ↗

Genetic polymorphism analysis of the drug-metabolizing enzyme CYP1A2 in a Uyghur Chinese population: a pilot study.Semantic proximity Read ↗

Gender and ethnicity modify the association between the CYP1A2 rs762551 polymorphism and habitual coffee intake: evidence from a meta-analysis.Semantic proximity Read ↗

Impact of smoking, smoking cessation, and genetic polymorphisms on CYP1A2 activity and inducibility.Semantic proximity Read ↗

Polymorphisms in the CYP1A2 gene and theophylline metabolism in patients with asthma.Semantic proximity Read ↗

Detailed modelling of caffeine metabolism and examination of the CYP1A2 gene: lack of a polymorphism in CYP1A2 in Caucasians.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.