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Article

Phenotype-genotype analysis of CYP1A2 in Japanese patients receiving oral theophylline therapy.

European journal of clinical pharmacology - 1 Jan 2006

Takata Keiji, Saruwatari Junji, Nakada Naoyuki, Nakagawa Mizuna, Fukuda Koichiro, Tanaka Fujiho, Takenaka Shinobu, Mihara Shuichi, Marubayashi Toru, Nakagawa Kazuko

Abstract excerpt

OBJECTIVE: To clarify the association between the cytochrome P450 (CYP) 1A2 genotype with the CYP1A2 phenotype and to search for the CYP1A2*1K haplotype, which has been shown to decrease CYP1A2 inducibility and/or other functional polymorphisms in Japanese. METHODS: Two polymorphisms, CYP1A2*1C and CYP1A2*1F, were genotyped in 126 patients receiving oral slow-release theophylline (TP) therapy and in 224 healthy...

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Identifiers

PMID: 16385402
DOI: 10.1007/s00228-005-0057-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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