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Influence of genetic polymorphisms, smoking, gender and age on CYP1A2 activity in a Turkish population.

Pharmacogenomics - 1 May 2009

Gunes Arzu, Ozbey Gul, Vural Elif Hilal, Uluoglu Canan, Scordo Maria Gabriella, Zengil Hakan, Dahl Marja-Liisa

Abstract excerpt

AIMS: To study the variation in CYP1A2 activity in relation to smoking, gender, age and CYP1A2 polymorphisms. MATERIALS & METHODS: CYP1A2 activity was determined by plasma paraxanthine:caffeine ratio (17X:137X) 4 h after the intake of a standardized cup of coffee in 146 Turkish healthy volunteers. Seven CYP1A2 polymorphisms (-3860G>A, -3113G>A, -2467del/T, -739T>G, -729C>T, -163C>A and 5347T>C) were analyzed....

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Identifiers

PMID: 19450128
DOI: 10.2217/pgs.09.22

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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