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Article

Phenotypic polymorphism and gender-related differences of CYP1A2 activity in a Chinese population.

British journal of clinical pharmacology - 1 Feb 2000

Ou-Yang D S, Huang S L, Wang W, Xie H G, Xu Z H, Shu Y, Zhou H H

Abstract excerpt

AIMS: To investigate the distribution characteristics of CYP1A2 in a Chinese population, and to examine gender-related differences in CYP1A2 activity. METHODS: Two hundred and twenty-nine healthy subjects, 120 men and 109 women, were enrolled in this study. CYP1A2 activity was measured by plasma paraxanthine/caffeine (1,7X/1,3,7X) ratio 6 h after administration of 300 mg caffeine. The concentrations of...

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Identifiers

PMID: 10671909
DOI: 10.1046/j.1365-2125.2000.00128.x
PMCID: PMC2014904

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Source receipt: pubmed, retrieved 7 Sept 2026.

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