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Article

Downregulation of KLF4 and the Bcl-2/Bax ratio in advanced epithelial ovarian cancer

30 Jul 2012

Abstract excerpt

Kruppel-like factor 4 (KLF4) is a key transcriptional regulator of cell differentiation and proliferation and an altered expression of KLF4 has been reported in a number of human malignancies. In the present study, we investigated KLF4 expression and its role in cell proliferation in advanced epithelial ovarian cancer (EOC). We compared KLF4, Bcl-2 and Bax transcript levels in ovaries isolated from advanced EOC...

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PMID: 23162646
DOI: 10.3892/ol.2012.834

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