Article
Gene expression profiling, prognosis, and immune microenvironment of KLF4 in malignancies.
PloS one - 1 Jan 2025
Yu Shoukai, Qian Lingmei, Tong Tianlang, Ma Xujun
Abstract excerpt
Gene expression profiling plays a crucial role in understanding the role of Krüppel-like factor 4 (KLF4) in the prognosis and tumor immune microenvironment of various malignancies. The transcription factor KLF4 plays a crucial role in various cellular processes, including cell differentiation, proliferation, and apoptosis. Genetic alterations and aberrant KLF4 expression have been observed in many malignancies,...
Read the complete abstract on PubMedTopics
- Kruppel-Like Factor 4
- Humans
- Kruppel-Like Transcription Factors
- Prognosis
- Neoplasms
- Gene Expression Profiling
- Tumor Microenvironment
