Article
Elevated Krüppel-like factor 4 transcription factor in canine mammary carcinoma.
BMC veterinary research - 7 Oct 2011
Chu Pei-Yi, Hsu Nicholas Chung-Heng, Liao Albert Taiching, Yeh Kun-Tu, Hou Ming-Feng, Liu Chen-Hsuan
Abstract excerpt
BACKGROUND: Krüppel-like factors (KLFs) are critical regulators of biological and physiological systems and have been extensively studied for their roles in cell proliferation, differentiation and survival in the context of cancer. Among the KLFs, KLF4 is highly expressed in human breast cancers and plays an oncogenic role. The present study examined the expression of KLF4 and assessed its significance in canine...
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