Article
Exact genetic linkage computations for general pedigrees.
Bioinformatics (Oxford, England) - 1 Jan 2002
Fishelson M, Geiger D
Abstract excerpt
MOTIVATION: Genetic linkage analysis is a useful statistical tool for mapping disease genes and for associating functionality of genes with their location on the chromosome. There is a need for a program that computes multipoint likelihood on general pedigrees with many markers that also deals with two-locus disease models. RESULTS: In this paper we present algorithms for performing exact multipoint likelihood...
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