Article
Maximum likelihood haplotyping for general pedigrees.
Human heredity - 1 Jan 2005
Fishelson Ma'ayan, Dovgolevsky Nickolay, Geiger Dan
Abstract excerpt
Haplotype data is valuable in mapping disease-susceptibility genes in the study of Mendelian and complex diseases. We present algorithms for inferring a most likely haplotype configuration for general pedigrees, implemented in the newest version of the genetic linkage analysis system SUPERLINK. In SUPERLINK, genetic linkage analysis problems are represented internally using Bayesian networks. The use of Bayesian...
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