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High-throughput SNP analysis for genetic association studies.

Current opinion in drug discovery & development - 1 May 2003

Marnellos George

Abstract excerpt

Single nucleotide polymorphisms (SNPs) are the most common type of genetic variation, and millions of SNPs are now documented. Because of their dense distribution across the genome, SNPs are viewed as ideal markers for large-scale genome-wide association studies to discover genes in common complex diseases, such as cancer. To enable such studies, researchers have constructed appropriate sets of SNP markers, by...

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PMID: 12833663

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