Article
The transcriptional regulator lola is required for stem cell maintenance and germ cell differentiation in the Drosophila testis.
Developmental biology - 15 Jan 2013
Davies Erin L, Lim Jaclyn G Y, Joo William J, Tam Cheuk Ho, Fuller Margaret T
Abstract excerpt
Stem cell behavior is regulated by extrinsic signals from specialized microenvironments, or niches, and intrinsic factors required for execution of context-appropriate responses to niche signals. Here we show that function of the transcriptional regulator longitudinals lacking (lola) is required cell autonomously for germline stem cell and somatic cyst stem cell maintenance in the Drosophila testis. In addition,...
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