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Article

Lasp anchors the Drosophila male stem cell niche and mediates spermatid individualization.

Mechanisms of development - 1 Jan 2000

Lee Soojin, Zhou Lili, Kim Jieun, Kalbfleisch Stephen, Schöck Frieder

Abstract excerpt

Lasp family proteins contain an amino-terminal LIM domain, two actin-binding nebulin repeats and a carboxyl-terminal SH3 domain. Vertebrate Lasp-1 localizes to focal adhesions and the leading edge of migrating cells, and is required for cell migration. To assess the in vivo function of Lasp, we generated a null mutant in Drosophila Lasp. Lasp(1) is homozygous viable, but male sterile. In Lasp mutants the stem...

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Identifiers

PMID: 18655828
DOI: 10.1016/j.mod.2008.06.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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