Article
Whole-genome sequencing to delineate Mycobacterium tuberculosis outbreaks: a retrospective observational study.
The Lancet. Infectious diseases - 1 Feb 2013
Walker Timothy M, Ip Camilla L C, Harrell Ruth H, Evans Jason T, Kapatai Georgia, Dedicoat Martin J, Eyre David W, Wilson Daniel J, Hawkey Peter M, Crook Derrick W, Parkhill Julian, Harris David, Walker A Sarah, Bowden Rory, Monk Philip, Smith E Grace, Peto Tim E A
Abstract excerpt
BACKGROUND: Tuberculosis incidence in the UK has risen in the past decade. Disease control depends on epidemiological data, which can be difficult to obtain. Whole-genome sequencing can detect microevolution within Mycobacterium tuberculosis strains. We aimed to estimate the genetic diversity of related M tuberculosis strains in the UK Midlands and to investigate how this measurement might be used to investigate...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.