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Article

An integrated computational environment for elementary modes analysis of biochemical networks.

International journal of data mining and bioinformatics - 1 Jan 2012

Maia Paulo, Vilaça Paulo, Rocha Isabel, Pont Marcellinus, Tomb Jean-François, Rocha Miguel

Abstract excerpt

Elementary flux modes (EFMs) have been claimed as one of the most promising approaches for pathway analysis. These are a set of vectors that emerge from the stoichiometric matrix of a biochemical network through the use of convex analysis. The computation of all EFMs of a given network is an NP-hard problem and existing algorithms do not scale well. Moreover, the analysis of results is difficult given the...

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Identifiers

PMID: 23155769
DOI: 10.1504/ijdmb.2012.049292

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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