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Article

Capturing the essence of a metabolic network: a flux balance analysis approach.

Journal of theoretical biology - 7 Oct 2009

Murabito Ettore, Simeonidis Evangelos, Smallbone Kieran, Swinton Jonathan

Abstract excerpt

As genome-scale metabolic reconstructions emerge, tools to manage their size and complexity will be increasingly important. Flux balance analysis (FBA) is a constraint-based approach widely used to study the metabolic capabilities of cellular or subcellular systems. FBA problems are highly underdetermined and many different phenotypes can satisfy any set of constraints through which the metabolic system is...

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PMID: 19540851
DOI: 10.1016/j.jtbi.2009.06.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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