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Combining pathway analysis with flux balance analysis for the comprehensive study of metabolic systems.

Biotechnology and bioengineering - 1 Jan 2000

Schilling C H, Edwards J S, Letscher D, Palsson B Ø

Abstract excerpt

The elucidation of organism-scale metabolic networks necessitates the development of integrative methods to analyze and interpret the systemic properties of cellular metabolism. A shift in emphasis from single metabolic reactions to systemically defined pathways is one consequence of such an integrative analysis of metabolic systems. The constraints of systemic stoichiometry, and limited thermodynamics have led...

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PMID: 11291038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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