Utilizing elementary mode analysis, pathway thermodynamics, and a genetic algorithm for metabolic flux determination and optimal metabolic network design.

Abstract excerpt

BACKGROUND: Microbial hosts offer a number of unique advantages when used as production systems for both native and heterologous small-molecules. These advantages include high selectivity and benign environmental impact; however, a principal drawback is low yield and/or productivity, which limits economic viability. Therefore a major challenge in developing a microbial production system is to maximize formation...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biomass
• Share to Carbon
• Share to Carotenoids