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Article

Cytochrome P450 subfamily 2J polypeptide 2 expression and circulating epoxyeicosatrienoic metabolites in preeclampsia.

Circulation - 18 Dec 2012

Herse Florian, Lamarca Babbette, Hubel Carl A, Kaartokallio Tea, Lokki A Inkeri, Ekholm Eeva, Laivuori Hannele, Gauster Martin, Huppertz Berthold, Sugulle Meryam, Ryan Michael J, Novotny Sarah, Brewer Justin, Park Joon-Keun, Kacik Michael, Hoyer Joachim, Verlohren Stefan, Wallukat Gerd, Rothe Michael, Luft Friedrich C, Muller Dominik N, Schunck Wolf-Hagen, Staff Anne C, Dechend Ralf

Abstract excerpt

BACKGROUND: Preeclampsia is a multisystem disorder of pregnancy, originating in the placenta. Cytochrome P450 (CYP)-dependent eicosanoids regulate vascular function, inflammation, and angiogenesis, which are mechanistically important in preeclampsia. METHODS AND RESULTS: We performed microarray s...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23155181
DOI: 10.1161/CIRCULATIONAHA.112.127340
PMCID: PMC3543781

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23155181-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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