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Article

Glutamate system genes and brain volume alterations in pediatric obsessive-compulsive disorder: a preliminary study.

Psychiatry research - 30 Mar 2013

Wu Ke, Hanna Gregory L, Easter Philip, Kennedy James L, Rosenberg David R, Arnold Paul D

Abstract excerpt

Obsessive-compulsive disorder (OCD) has been associated with regional volumetric brain abnormalities, which provide promising intermediate phenotypes of the disorder. In this study, volumes of brain regions selected for a priori evidence of association with OCD (orbitofrontal cortex (OFC), anterior cingulate cortex (ACC), thalamus, caudate, putamen, globus pallidus and pituitary) were measured using structural...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23154099
DOI: 10.1016/j.pscychresns.2012.07.003
PMCID: PMC4552325

Genes

DLGAP2
DLGAP1
DLGAP3
GRIK2
GRIK3
SLITRK1
SLITRK5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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