Article
Association of rs11081062 polymorphism of DLGAP1 gene and levels of SLC1A1 protein with obsessive-compulsive disorder.
Nucleosides, nucleotides & nucleic acids - 1 Jan 2024
Akkuş Efruz İrem, Bayoğlu Burcu, Kocabaşoğlu Neşe, Yıldız Jansed Berfin, Cengiz Müjgan
Abstract excerpt
Glutamate is an important neurotransmitter known to be effective in obsessive-compulsive disorder (OCD). The aim of this study is to investigate the relationship between the DLGAP1 gene encoding the scaffold protein of ionotropic glutamate receptors and the SLC1A1 gene encoding the glutamate transporter protein with OCD. Study groups consisted of 95 patients with OCD and 100 healthy controls. The severity of OCD...
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