Article

Transcriptomes of higher order thalamic nuclei in obsessive compulsive disorder

2025-04-23

Abstract excerpt

Obsessive-compulsive disorder (OCD) is a chronic psychiatric illness associated with altered function in cortico-striatal-thalamo-cortical (CSTC) circuits. In this pilot study, we examined differential RNA expression in the thalamus using postmortem human brain tissue samples from 11 subjects with OCD and 10 unaffected subjects. We individually dissected the mediodorsal magnocellular, mediodorsal parvocellular, an...

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Literature Corpus work: e8df14e4-a9a4-5ed9-9859-6aafcc46db15
DOI: 10.1101/2025.04.22.650032

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