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Article

Association between polymorphisms in GRIK2 gene and obsessive-compulsive disorder: a family-based study.

CNS neuroscience & therapeutics - 1 Jun 2011

Sampaio Aline S, Fagerness Jesen, Crane Jacquelyn, Leboyer Marion, Delorme Richard, Pauls David L, Stewart S Evelyn

Abstract excerpt

Several studies support a genetic influence on obsessive-compulsive disorder (OCD) etiology. The role of glutamate as an important neurotransmitter affecting OCD pathophysiology has been supported by neuroimaging, animal model, medication, and initial candidate gene studies. Genes involved in glutamatergic pathways, such as the glutamate receptor, ionotropic, kainate 2 (GRIK2), have been associated with OCD in...

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Identifiers

PMID: 20370803
DOI: 10.1111/j.1755-5949.2009.00130.x
PMCID: PMC6493828

Genes

GRIK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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