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Article

A novel strategy for efficient production of anti-V3 human scFvs against HIV-1 clade C.

BMC biotechnology - 15 Nov 2012

Kumar Rajesh, Andrabi Raiees, Tiwari Ashutosh, Prakash Somi Sankaran, Wig Naveet, Dutta Durgashree, Sankhyan Anurag, Khan Lubina, Sinha Subrata, Luthra Kalpana

Abstract excerpt

BACKGROUND: Production of human monoclonal antibodies that exhibit broadly neutralizing activity is needed for preventing HIV-1 infection, however only a few such antibodies have been generated till date. Isolation of antibodies by the hybridoma technology is a cumbersome process with fewer yields. Further, the loss of unstable or slowly growing clones which may have unique binding specificities often occurs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23153214
DOI: 10.1186/1472-6750-12-87
PMCID: PMC3536577

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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