Article
MDR1 in paroxetine-induced sexual dysfunction.
Journal of sex & marital therapy - 1 Jan 2013
Zourková Alexandra, Slanař Ondřej, Jarkovský Jiří, Palčíková Ivana, Pindurová Eva, Cvanová Michaela
Abstract excerpt
Paroxetine-induced sexual dysfunction represents a frequent treatment complication of otherwise efficient antidepressants. The genetic polymorphism of pharmacokinetic genes may contribute to the occurrence of such dysfunctions. This study presents the effect of MDR1 gene polymorphisms on sexual function in 18 women with bulimia nervosa, 18 women with anxiety disorders, and 19 healthy control subjects. It also...
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