Article
Association between serotonin 2A receptor (HTR2A), serotonin transporter (SLC6A4) and brain-derived neurotrophic factor (BDNF) gene polymorphisms and citalopram/sertraline induced sexual dysfunction in MDD patients.
The pharmacogenomics journal - 1 Jun 2020
Oz Merve Demirbugen, Baskak Bora, Uckun Zuhal, Artun Nazan Yuce, Ozdemir Hatice, Ozel Tugba Kizil, Ozguven Halise Devrimci, Suzen H Sinan
Abstract excerpt
Sexual dysfunction (SD) is a troublesome adverse effect of selective serotonin reuptake inhibitors (SSRIs). A variety of mechanisms might be involved in the occurrence of SD but the exact mechanism is still not clear. Genetic variations among patients treated with SSRIs are strong determinants of intolerance and poor compliance. The present study aimed to determine the relationship between serotonin-2A receptor...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.