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Article

Naltrexone Use in Treating Hypersexuality Induced by Dopamine Replacement Therapy: Impact of OPRM1 A/G Polymorphism on Its Effectiveness.

International journal of molecular sciences - 24 Apr 2020

Verholleman Audrey, Victorri-Vigneau Caroline, Laforgue Edouard, Derkinderen Pascal, Verstuyft Celine, Grall-Bronnec Marie

Abstract excerpt

Hypersexuality is a well-known adverse side effect of dopamine replacement therapy (DRT), and anti-craving drugs could be an effective therapeutic option. Our aim was to update the knowledge on this issue, particularly on the influence of an Opioid Receptor Mu 1 (OPRM1) genetic polymorphism. A systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32344532
DOI: 10.3390/ijms21083002
PMCID: PMC7215378

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