Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Straightforward Selection of Broadly Neutralizing Single-Domain Antibodies Targeting the Conserved CD4 and Coreceptor Binding Sites of HIV-1 gp120

14 Nov 2012

Abstract excerpt

Few broadly neutralizing antibodies targeting determinants of the HIV-1 surface envelope glycoprotein (gp120) involved in sequential binding to host CD4 and chemokine receptors have been characterized. While these epitopes show low diversity among various isolates, HIV-1 employs many strategies to evade humoral immune response toward these sensitive sites, including a carbohydrate shield, low accessibility to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV Research and Treatment
Share to Immune Cell Function and Interaction
Share to Monoclonal and Polyclonal Antibodies Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23152508
DOI: 10.1128/jvi.00461-12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Straightforward Selection of Broadly Neutralizing Single-Domain Antibodies Targeting the Conserved CD4 and Coreceptor Binding Sites of HIV-1 gp120PMID 23152508Read ↗

A multidonor class of highly glycan-dependent HIV-1 gp120-gp41 interface-targeting broadly neutralizing antibodiesSemantic proximity Read ↗

Antibodies Targeting the Envelope of HIV-1.Semantic proximity Read ↗

Light chain of a public SARS-CoV-2 class-3 antibody modulates neutralization against OmicronSemantic proximity Read ↗

Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoproteinSemantic proximity Read ↗

Broadly Neutralizing Antibodies for HIV EradicationSemantic proximity Read ↗

Generation of a family-specific phage library of llama single chain antibody fragments that neutralize HIV-1.Semantic proximity Read ↗

Profiling a large HIV-1 elite neutralizer cohort reveals remarkable CD4bs bNAb for HIV-1 prevention and therapySemantic proximity Read ↗

Llama Antibody Fragments with Cross-Subtype Human Immunodeficiency Virus Type 1 (HIV-1)-Neutralizing Properties and High Affinity for HIV-1 gp120Semantic proximity Read ↗

Structural basis for germline gene usage of a potent class of antibodies targeting the CD4 binding site of HIV-1 gp120Semantic proximity Read ↗

Broadly Neutralizing Antibodies against HIV-1 As a Novel Aspect of the Immune ResponseSemantic proximity Read ↗

Mining HIV controllers for broad and functional antibodies to recognize and eliminate HIV-infected cellsSemantic proximity Read ↗

Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.