Article
Epigenetic regulation of cancer stem cell gene expression.
Sub-cellular biochemistry - 1 Jan 2013
Bapat Sharmila A
Abstract excerpt
The concept of cancer as a stem cell disease has slowly gained ground over the last decade. A 'stem-like' state essentially necessitates that some cells in the developing tumor express the properties of remaining quiescent, self-renewing and regenerating tumors through establishment of aberrant cellular hierarchies. Alternatively, such capacities may also be reacquired through a de-differentiation process. The...
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