Article
Neoplastic stem cells: a novel therapeutic target in clinical oncology.
Cancer - 15 Nov 2006
Schulenburg Axel, Ulrich-Pur Herbert, Thurnher Dietmar, Erovic Boban, Florian Stefan, Sperr Wolfgang R, Kalhs Peter, Marian Brigitte, Wrba Friedrich, Zielinski Christoph C, Valent Peter
Abstract excerpt
Cancer is among the leading causes of morbidity and mortality in the Western world. Despite recent advances, most therapeutic approaches fail to eradicate the entire neoplastic clone. The remaining cells often develop metastasis and/or recurrences and therefore may represent attractive targets of therapy. A new exciting concept in this regard suggests that each neoplasm represents a heterogeneous population of...
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