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Stemming Cancer: Functional Genomics of Cancer Stem Cells in Solid Tumors

16 Jun 2008

Abstract excerpt

Cancer stem cells (CSCs) were discovered about 15 years ago in hematopoietic cancers. Subsequently, cancer stem cells were discovered in various solid tumors. Based on parallels with normal stem cells, a developmental process of cancer stem cells follows paths of organized, hierarchical structure of cells with different degrees of maturity. While some investigators have reported particular markers as...

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PMID: 18561035
DOI: 10.1007/s12015-008-9034-0

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