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Article

Mechanisms that mediate stem cell self‐renewal and differentiation

23 Jul 2007

Abstract excerpt

Stem cells have two common properties: the capacity for self-renewal and the potential to differentiate into one or more specialized cell types. In general, stem cells can be divided into two broad categories: adult (somatic) stem cells and embryonic stem cells. Recent evidence suggested that tumors may contain "cancer stem cells" with indefinite potential for self-renewal. In this review, we will focus on the...

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PMID: 17647265
DOI: 10.1002/jcb.21460

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