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Article

Molecular analysis of desmoid tumors with a high-density single-nucleotide polymorphism array identifies new molecular candidate lesions.

Onkologie - 1 Jan 2012

Erben Philipp, Nowak Daniel, Sauer Christian, Ströbel Philipp, Hofmann Wolf-Karsten, Hofheinz Ralf-Dieter, Hohenberger Peter, Kasper Bernd

Abstract excerpt

BACKGROUND: Desmoid tumors are neoplastic proliferations of connective tissues. The mutation status of the gene coding for catenin (cadherin-associated protein) beta 1 (CTNNB1) and trisomy 8 on the chromosomal level have been described to have prognostic relevance. PATIENTS AND METHODS: In order to elucidate new molecular mechanisms underlying these tumors, we carried out a molecular analysis with a genome-wide...

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Source

Identifiers

PMID: 23147545
DOI: 10.1159/000343744

Genes

CSMD1
APC
CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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