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Adult desmoid tumors: biology, management and ongoing trials

9 May 2017

Abstract excerpt

PURPOSE OF REVIEW: To summarize the current knowledge about the biology and clinical management of adult desmoid tumors. RECENT FINDINGS: In the past decade, we have learned that desmoid tumors are driven by alterations of the Wnt/APC/β-catenin pathway, sporadic desmoid tumors are associated with somatic mutations of CTNNB1, and germline mutations of APC and somatic mutations of CTNNB1 are probably mutually...

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PMID: 28489620
DOI: 10.1097/cco.0000000000000374

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