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Article

Paradigm shifts in cardiovascular research from Caenorhabditis elegans muscle.

Trends in cardiovascular medicine - 1 Nov 2012

Epstein Henry F, Benian Guy M

Abstract excerpt

Research on Caenorhabditis elegans has led to the discovery of the consequences of mutation in myosin, its associated proteins, and the extracellular matrix-membrane cytoskeleton complex. Key results include understanding thick filament structure and assembly, the regulation of sarcomeric protein turnover, and the organization of thick and thin filaments into ordered sarcomeres. These results are critical to...

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Identifiers

PMID: 23146617
DOI: 10.1016/j.tcm.2012.07.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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