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Article

Genes critical for muscle development and function in Caenorhabditis elegans identified through lethal mutations.

The Journal of cell biology - 1 Feb 1994

Williams B D, Waterston R H

Abstract excerpt

By taking advantage of a lethal phenotype characteristic of Caenorhabditis elegans embryos that fail to move, we have identified 13 genes required for muscle assembly and function and discovered a new lethal class of alleles for three previously known muscle-affecting genes. By staining mutant embryos for myosin and actin we have recognized five distinct classes of genes: mutations in four genes disrupt the...

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Identifiers

PMID: 8106547
DOI: 10.1083/jcb.124.4.475
PMCID: PMC2119919

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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