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Spectrin regulates cell contractility through production and maintenance of actin bundles in theCaenorhabditis elegansspermatheca

9 Aug 2018

Abstract excerpt

Disruption to the contractility of cells, including smooth muscle cells of the cardiovascular system and myoepithelial cells of the glandular epithelium, contributes to the pathophysiology of contractile tissue diseases, including asthma, hypertension, and primary Sjögren's syndrome. Cell contractility is determined by myosin activity and actomyosin network organization and is mediated by hundreds of...

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PMID: 30091661
DOI: 10.1091/mbc.e18-06-0347

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