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Article

Phenotyping cardiomyopathy in adult zebrafish.

Progress in biophysics and molecular biology - 1 Oct 2018

Dvornikov Alexey V, de Tombe Pieter P, Xu Xiaolei

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) is usually manifested by increased myofilament Ca2+ sensitivity, excessive contractility, and impaired relaxation. In contrast, dilated cardiomyopathy (DCM) originates from insufficient sarcomere contractility and reduced cardiac pump function, subsequently resulting in heart failure. The zebrafish has emerged as a new model of human cardiomyopathy with high-throughput screening,...

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Identifiers

PMID: 29884423
DOI: 10.1016/j.pbiomolbio.2018.05.013
PMCID: PMC6269218

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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