Article
Ondansetron and sertraline may interact with 5-HTTLPR and DRD4 polymorphisms to reduce drinking in non-treatment seeking alcohol-dependent women: exploratory findings.
Alcohol (Fayetteville, N.Y.) - 1 Sept 2014
Kenna George A, Zywiak William H, Swift Robert M, McGeary John E, Clifford James S, Shoaff Jessica R, Fricchione Samuel, Brickley Michael, Beaucage Kayla, Haass-Koffler Carolina L, Leggio Lorenzo
Abstract excerpt
The purpose of this exploratory study was to examine the interaction of 5-HTTLPR and DRD4 exon III polymorphisms with gender in non-treatment seeking alcohol-dependent (AD) individuals while alternately taking ondansetron and sertraline. Evidence suggests that alcohol dependence may be influenced by a genetic interaction that may be gender-specific with temporal changes making pharmacological treatment with...
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