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Article

A within-group design of nontreatment seeking 5-HTTLPR genotyped alcohol-dependent subjects receiving ondansetron and sertraline.

Alcoholism, clinical and experimental research - 1 Feb 2009

Kenna George A, Zywiak William H, McGeary John E, Leggio Lorenzo, McGeary Chinatsu, Wang Shirley, Grenga Andrea, Swift Robert M

Abstract excerpt

BACKGROUND: Serotonergic mechanisms are associated with the development of alcohol dependence (AD), however, studies evaluating serotonergic medications have produced conflicting results. One hypothesis suggests that differential response may be due to a functional polymorphism of the 5-HTTLPR promoter region of the serotonin re-uptake transporter (5-HTT). The L/L genotype is postulated to be associated with...

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Source

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Identifiers

PMID: 19032576
DOI: 10.1111/j.1530-0277.2008.00835.x
PMCID: PMC5567679

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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