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Article

Equine cytochrome P450 2B6--genomic identification, expression and functional characterization with ketamine.

Toxicology and applied pharmacology - 1 Jan 2013

Peters L M, Demmel S, Pusch G, Buters J T M, Thormann W, Zielinski J, Leeb T, Mevissen M, Schmitz A

Abstract excerpt

Ketamine is an anesthetic and analgesic regularly used in veterinary patients. As ketamine is almost always administered in combination with other drugs, interactions between ketamine and other drugs bear the risk of either adverse effects or diminished efficacy. Since cytochrome P450 enzymes (CYPs) play a pivotal role in the phase I metabolism of the majority of all marketed drugs, drug-drug interactions often...

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PMID: 23142468
DOI: 10.1016/j.taap.2012.10.028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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