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Article

Model animals for the study of oxidative stress from complex II.

Biochimica et biophysica acta - 1 May 2013

Ishii Takamasa, Miyazawa Masaki, Onouchi Hiromi, Yasuda Kayo, Hartman Phil S, Ishii Naoaki

Abstract excerpt

Mitochondria play a role of energy production and produce intracellular reactive oxygen species (ROS), especially superoxide anion (O2(-)) as a byproduct of energy metabolism at the same time. O2(-) is converted from oxygen and is overproduced by excessive electron leakage from the mitochondrial respiratory chain. It is well known that mitochondrial complexes I and III in the electron transport system are the...

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Identifiers

PMID: 23142169
DOI: 10.1016/j.bbabio.2012.10.016

Genes

SDHC
SDHB
SDHD

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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