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Article

Mitochondrial superoxide anion (O(2)(-)) inducible "mev-1" animal models for aging research.

BMB reports - 1 May 2011

Ishii Takamasa, Miyazawa Masaki, Hartman Phil S, Ishii Naoaki

Abstract excerpt

Most intracellular reactive oxygen species (ROS), especially superoxide anion (O(2)(-)) that is converted from oxygen, are overproduced by excessive electron leakage from the mitochondrial respiratory chain. Intracellular oxidative stress that damages cellular components can contribute to lifestyle-related diseases such as diabetes and arteriosclerosis, and age-related diseases such as cancer and neuronal...

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Source

Identifiers

PMID: 21615983
DOI: 10.5483/BMBRep.2011.44.5.298

Genes

SDHC
SDHB
SDHD

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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