Article
M-cadherin-inhibited phosphorylation of ß-catenin augments differentiation of mouse myoblasts.
Cell and tissue research - 1 Jan 2013
Wang Yan, Mohamed Junaith S, Alway Stephen E
Abstract excerpt
β-Catenin is essential for muscle development because it regulates both cadherin-mediated cell-cell adhesion and canonical Wingless and Int1 (Wnt) signaling. The phosphorylation of β-catenin by glycogen synthase kinase-3β (GSK-3β) at serine31/37/threonine41 regulates its stability and its role in canonical Wnt signaling. In this study, we have investigated whether the N-terminal phosphorylation of β-catenin is...
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