Article
Novel connexin40 missense mutations in patients with familial atrial fibrillation.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology - 1 Oct 2010
Yang Yi-Qing, Liu Xu, Zhang Xian-Ling, Wang Xin-Hua, Tan Hong-Wei, Shi Hai-Feng, Jiang Wei-Feng, Fang Wei-Yi
Abstract excerpt
AIMS: This research was aimed at screening connexin40, a cardiac gap junction protein alpha 5, for genetic defects in patients with familial atrial fibrillation (AF). METHODS: The subjects included 218 unrelated families with lone AF and 200 ethnically matched unrelated healthy individuals as controls. The entire coding region of the connexin40 gene was sequenced initially in 218 unrelated probands with familial...
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