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Article

Structural insights into the inhibition of actin-capping protein by interactions with phosphatidic acid and phosphatidylinositol (4,5)-bisphosphate.

PLoS computational biology - 1 Jan 2012

Pleskot Roman, Pejchar Přemysl, Žárský Viktor, Staiger Christopher J, Potocký Martin

Abstract excerpt

The actin cytoskeleton is a dynamic structure that coordinates numerous fundamental processes in eukaryotic cells. Dozens of actin-binding proteins are known to be involved in the regulation of actin filament organization or turnover and many of these are stimulus-response regulators of phospholipid signaling. One of these proteins is the heterodimeric actin-capping protein (CP) which binds the barbed end of...

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PMID: 23133367
DOI: 10.1371/journal.pcbi.1002765
PMCID: PMC3486809

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PIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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